Accessed March 26, 2020. The condition often causes no symptoms, but some women may have nipple discharge, breast tenderness or inflammation of the clogged duct (periductal mastitis). This can cause the duct to become blocked and lead to fluid build-up. Duct ectasia, also known as mammary duct ectasia, is a benign (non-cancerous) breast condition that occurs when a milk duct in the breast widens and its walls thicken. Histologically, dilation of the large duct is prominent. 5th ed. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. At the American Cancer Society, we’re on a mission to free the world from cancer. American Cancer Society. Research. If symptoms persist, you may need antibiotics or possibly surgery to remove the affected milk duct. The term duct ectasia syndrome has been used to describe symptoms of nonpuerperal mastitis, possibly associated with nipple inversion and nipple discharge. Duct ectasia, also known as mammary duct ectasia, is a benign (non-cancerous) breast condition that occurs when a milk duct in the breast widens and its walls thicken. Accessed March 27, 2020. This site complies with the HONcode standard for trustworthy health information: verify here. An ultrasound and/or mammogram may be done to learn more about the changed part of your breast. The American Cancer Society couldn’t do what we do without the support of our partners. Duct ectasia syndrome in the classical meaning is associated with additional histological changes. Guray M, Sahin AA. European Journal of Breast Health. Mammary duct ectasia can mimic breast cancer. If there’s a lump, a biopsy may be needed to make sure it’s not cancer. Smokers seem more often affected by duct ectasia syndrome although the reported results are not entirely consistent. Cancer Information, Answers, and Hope. Abscessation is not very frequent but by some definitions recurrent subareolar abscess is merely a variant of duct ectasia syndrome - abscessation would be obviously more frequent with this definition. Advertising revenue supports our not-for-profit mission. From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. Correlation with the actual duct widening is not known. Mammary duct ectasia happens when one or more milk ducts under the nipple dilate (or get wider) and its walls thicken. Though it's normal to worry about any changes in your breasts, mammary duct ectasia and periductal mastitis aren't risk factors for breast cancer. The fluid may leak into the tissue surrounding the duct, and the tissue … See our safe care and visitor guidelines, plus trusted coronavirus information. All rights reserved. 2019. The process that causes the condition is still being debated but histologically it is characterised by dilation of major ducts in the subareolar region. Noninvasive methods to determine duct diameter in live patients are available only recently and it is not clear how the results should be compared with older results from biopsies. The term has several meanings on histological and symptomatic levels and on both levels usage overlaps with mastalgia, fibrocystic disease and specific sub- or superclasses of nonpuerperal mastitis. Rosai J. The condition often causes no symptoms, but some women may have nipple discharge, breast tenderness or inflammation of the clogged duct (periductal mastitis).Mammary duct ectasia most ofte… Duct ectasia does not increase your breast cancer risk. Mammary duct ectasia most often occurs in women during perimenopause — around age 45 to 55 years — but it can happen after menopause, too. The correlation with smoking status appears weaker than for subareolar abscess. Ductal ectasia is often asymptomatic, especially when benign. Mammary duct ectasia can mimic breast cancer. Signs of duct ectasia can include nipple retraction, inversion, pain,[4] and classic green-brown discharge. Help make it a reality. 2nd ed. However, duct widening was recently very strongly correlated with noncyclic breast pain. Duct ectasia of the breast is a noncancerous condition that results in clogged ducts around your nipple. Until we do, we’ll be funding and conducting research, sharing expert information, supporting patients, and spreading the word about prevention. In some cases, the duct can become blocked or clogged with a pasty, yellow-brown or greenish substance, leading to infection (a condition known as periductal mastitis). It may not cause any symptoms at all, but can occasionally cause the nipple to become pulled inwards (inverted) as the milk ducts become shorter and widened. If the symptoms do not go away, the abnormal duct may need to be removed with surgery. While this is not ideal for a definition it results from actual usage in international literature. In plasma cell rich lesions diagnosed on core biopsies, steroid-responsive IgG4-related mastitis can be identified by IgG/IgG4 immunostaining.[6]. Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter — Digital Edition, FREE book offer – Mayo Clinic Health Letter. In addition to nonspecific duct widening the myoepithelial cell layer is atrophic, missing or replaced by fibrous tissue. Mammary duct ectasia. Philadelphia, Pa: Lippincott Williams & Wilkins; 2014. Benign duct ectasia is characterized by chronic inflammatory and fibrotic changes. For reprint requests, please see our Content Usage Policy. Simple duct widening should be carefully distinguished from more complex histological changes. It’s more common in women who are getting close to menopause. The original cuboidal epithelial layer may be also severely impaired or missing. Typical usage in North America is a synonym of nonpuerperal mastitis, including the special cases of granulomatous mastitis, comedo mastitis, subareolar abscess with or without squamous metaplasia of lactiferous ducts and fistulation.[7]. © 2020 American Cancer Society, Inc. All rights reserved. Warm compresses and antibiotics may be used in some cases. Duct ectasia of the breast, mammary duct ectasia or plasma cell mastitis is a condition in which occurs when a milk duct beneath the nipple widens, the duct walls thicken and the duct fills with fluid. A hollow needle is used to take a tiny piece of tissue from the area so it can be checked in the lab for cancer cells. Breast infection: A review of diagnosis and management practices. March 27, 2020. These may include: Mayo Clinic does not endorse companies or products. The nipple and nearby breast tissue may be tender and red. You can help reduce your risk of cancer by making healthy choices like eating right, staying active and not smoking. Oncologist. Duct widening with associated periductal fibrosis is frequently included in the wastebasket definition of fibrocystic disease. What does it take to outsmart cancer? UpToDate. The duct may also fill with fluid and become blocked or clogged with a thick, sticky substance. Benign breast diseases: Classification, diagnosis, and management. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing. This is the most common cause of greenish discharge. Dixon JM, Pariser KM. Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, we’re here to help. The milk duct may become blocked or clogged with a thick, sticky substance. Make a donation. La ectasia ductal, también conocida como ectasia ductal mamaria, es una afección benigna (no cancerosa) de los senos que ocurre cuando un conducto de leche se ensancha y sus paredes se engrosan.Esto puede bloquear el conducto y ocasionar acumulación de líquido. Diagnosis. [3], Duct diameter is naturally variable, subject to hormonal interactions. It is a disorder of peri- or post-menopausal age.[2]. Inflammation may result. The condition often improves without treatment. Learn how and when to remove this template message, "Symptomatic and incidental mammary duct ectasia", "Mammary Duct Ectasia: Stanford University criteria", Adipomastia (lipomastia, pseudogynecomastia), https://en.wikipedia.org/w/index.php?title=Duct_ectasia_of_breast&oldid=946480482, Wikipedia articles needing reorganization from July 2012, Articles with unsourced statements from July 2012, Creative Commons Attribution-ShareAlike License. A nipple that's always been turned inward (inverted) usually isn't a medical concern. Sometimes scar tissue around the abnormal duct causes a hard lump that may be confused with cancer. Often, this condition causes no symptoms and is found when a biopsy (removal of small pieces of breast tissue to be checked under a microscope) is done for another breast problem. https://www.merckmanuals.com/professional/gynecology-and-obstetrics/breast-disorders/nipple-discharge. The condition is usually self-limiting, and thus not indicated for surgery. Duct ectasia is a benign, non- cancerous condition caused as breast tissue ages. Making Strides Against Breast Cancer Walks, Hyperplasia of the Breast (Ductal or Lobular). Diseases of the Breast. We can even find you a free ride to treatment or a free place to stay when treatment is far from home. We couldn’t do what we do without our volunteers and donors. Duct ectasia of the breast, mammary duct ectasia or plasma cell mastitis is a condition in which occurs when a milk duct beneath the nipple widens, the duct walls thicken and the duct fills with fluid. Accessed March 27, 2020. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. It may not cause any symptoms. Breast. Merck Manual Professional Version. Pruthi S (expert opinion). In: Breast Pathology. 2018; doi:10.5152/ejbh.2018.3871. Learn more about these partnerships and how you too can join us in our mission to save lives, celebrate lives, and lead the fight for a world without cancer. The ducts contain eosinophilic granular secretions and foamy histiocytes. Less often, duct ectasia may cause a nipple discharge, which is often sticky and thick. However, patients with ductal ectasia may present with nonspecific breast symptoms: nipple discharge; nipple retraction; pain/tenderness; palpable mass; Pathology. Dabbs DJ. Because research literature regarding duct ectasia is anything but abundant it is probably easiest to determine the exact meaning(s) intended by the respective authors on a case by case basis and this section can offer only a few hints. This content does not have an Arabic version. Your breasts are made up of connective tissues that include a system of tiny passages that carry milk to the nipples (milk ducts). more about the changed part of your breast. Mayo Clinic is a not-for-profit organization. Elsevier; 2018. https://www.clinicalkey.com. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Reactive and inflammatory conditions of the breast. Nipple discharge. Correlation of duct widening with the "classical" symptoms of duct ectasia syndrome is unclear. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. A single copy of these materials may be reprinted for noncommercial personal use only. Duct ectasia sometimes gets better without treatment. What cancer patients, their families, and caregivers need to know about the coronavirus. Chapter 9: Pathology of benign breast disorders. Experts don't know exactly what causes mammary duct ectasia. Imagine a world free from cancer. The milk duct may become blocked or clogged with a thick, sticky substance. The duct walls may thicken and fill with fluid, becoming blocked or clogged with a sticky substance. Collins LC, Schnitt SJ. All so you can live longer — and better. But a nipple that has recently turned inward should be checked by a doctor. We’ve invested more than $4.9 billion in cancer research since 1946, all to find more – and better – treatments, uncover factors that may cause cancer, and improve cancer patients’ quality of life. Duct ectasia syndrome is a synonym for nonpuerperal mastitis, but the term has also been occasionally used to describe special cases of fibrocystic diseases or mastalgia or as a wastebasket definition of benign breast disease. Make an appointment with your doctor if you notice changes in your breasts — such as a new breast lump, spontaneous nipple discharge, skin redness or inflammation, or an inverted nipple — that are persistent or that worry you. Our team of expert journalists brings you all angles of the cancer story – from breaking news and survivor stories to in-depth insights into cutting-edge research. Mammary duct ectasia (ek-TAY-zhuh) occurs when a milk duct beneath your nipple widens, the duct walls thicken and the duct fills with fluid. American Cancer Society medical information is copyrighted material. Both duct widening and duct ectasia syndrome are frequently bilateral, hence systemic causes are likely involved. This can cause the duct to become blocked and lead to fluid build-up. The American Cancer Society medical and editorial content team. nipple retraction, inversion, pain, green-brown discharge, nipple discharge, breast discomfort, infection, concern about breast cancer, mammary duct ectasia, plasma cell mastitis, This page was last edited on 20 March 2020, at 12:31. Mammary duct ectasia often doesn't cause any signs or symptoms, but some people experience: A bacterial infection called mastitis also may develop in the affected milk duct, causing breast tenderness, inflammation in the area around the nipple (areola) and fever. One of the symptoms of mammary duct ectasia is inverted nipples. Accessed at https://www.uptodate.com/contents/nonlactational-mastitis-in-adults on August 12, 2019. Nonlactational mastitis in adults. This is the most common cause of greenish discharge. Breasts are made up of fibrous connective tissues, which are made up of cells, fibers and a gel-like substance.[5]. In some contexts, it was used to describe a particular form of nonpuerperal mastitis coincident with fibrocystic disease, frequently involving pasty (coloured) nipple discharge, nipple retraction, retroareolar abscess and blue dome cysts. Boakes E, et al. This is a benign breast disease that can mimic invasive carcinoma clinically. Become a volunteer, make a tax-deductible donation, or participate in a fundraising event to help us save lives. Mayo Clinic. Duct ectasia syndrome has been associated with histopathological findings that are distinct from a simple duct widening. The duct walls may thicken, and the duct may fill with fluid. In: Rosai and Ackerman's Surgical Pathology. The American Cancer Society is a qualified 501(c)(3) tax-exempt organization. https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions/duct-ectasia.html. Mammary duct ectasia (ek-TAY-zhuh) occurs when one or more milk ducts beneath your nipple widens. Es más común en las mujeres que están próximas a la menopausia, aunque también puede ocurrir después de la menopausia. A dirty white, greenish or black nipple discharge from one or both nipples, Tenderness in the nipple or surrounding breast tissue (areola), A breast lump or thickening near the clogged duct. Characteristic calcifications are often visible on mammographic images. Signs and symptoms of mammary duct ectasia may improve on their own. Mammary duct ectasia usually causes no signs or symptoms, but some women may have nipple discharge, breast tenderness or inflammation of the clogged duct. It is a disorder of peri- or post-menopausal age. [1] Noncancerous breast conditions. Mammary duct ectasia occurs when a milk duct beneath the nipple widens. [citation needed]. The nipple may be pulled inward. However, because nonspecific duct widening is common it might be also coincidental finding in many processes. Whether you or someone you love has cancer, knowing what to expect can help you cope. But it can happen after menopause, too. 2006;11;435-449. It’s also important to follow recommended screening guidelines, which can help detect certain cancers early.
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